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Autopsy findings on Covid deaths in vaccinated individuals and the ongoing impact of the pandemic
  • Dr. McMillan discusses the autoimmune paradigm in relation to Covid for over four years. 0:04

  • Emphasizes that the pandemic is not over and a new wave may be approaching. 0:35

  • Raises the question of how vaccinated individuals can still die from severe Covid. 0:44

  • Dr. McMillan stresses the significance of being educated and prepared for future Covid waves. 1:58

  • Highlights the importance of autopsies in understanding the pathology of Covid-19. 3:00

  • References a recent nationwide autopsy study in the Netherlands on Covid-19 histology. 3:27

  • The study analyzed 1,833 eligible participants to gain valuable insights. 4:15

Understanding the mechanism of severe Covid-19 in vaccinated and unvaccinated individuals
  • Autopsy data did not differentiate between vaccinated and unvaccinated individuals. 4:27

  • Importance of autopsy in understanding pathology and treatment modalities. 5:12

  • Interferon signaling plays a key role in response to viruses. 6:24

  • Unvaccinated individuals with delayed interferon response are at risk of severe disease. 7:29

  • Vaccinated individuals may still experience severe disease despite circulating antibodies. 8:19

Analysis of autopsy reports comparing COVID-19 deaths in 2020 and 2021, highlighting differences in age, disease duration, and causes of death
  • Shift in age of death from 70 in 2020 to 66 in 2021, indicating a younger cohort. 9:19

  • Increase in disease duration from around day 11-12 in 2020 to day 12-32 in 2021, leading to longer ICU stays. 10:05

  • Primary cause of death in COVID-19 cases was acute respiratory distress syndrome (ARDS) in 50% of cases. 11:07

  • Lack of comprehensive research on lung pathology in vaccinated COVID-19 deaths, highlighting a gap in understanding. 12:10

  • Pathological findings include diffuse alveolar damage, fibrosis, thrombi, and microorganisms in the lungs. 12:45

Analysis of COVID-19 autopsies reveals critical findings on disease progression and potential mechanisms of death
  • Microthrombi in 8 to 14 days are crucial in severe COVID-19 pathology. 13:20

  • Acute diffuse alveolar edema occurs in 47% by 56 days, indicating disease progression. 14:13

  • Organizing diffuse alveolar damage similar to fibrosis appears early on in 41% by the second week. 14:24

  • Questions raised regarding autoimmune inflammatory processes in vaccinated individuals exposed to COVID-19. 15:00

  • Unvaccinated with natural immunity may still be at risk if interferon autoantibodies are present. 15:42

  • Importance of understanding how interferon response changes in vaccinated individuals exposed to the virus. 16:09

  • Comparison of autopsy findings between 2020 and 2021 suggests a potential impact of vaccination status on disease presentation. 17:08

Exploring the impact of an inflammatory process in the lungs of vaccinated individuals during the Covid-19 pandemic
  • Inflammatory process in the lungs may be exacerbated by infection, leading to higher pulmonary fibrosis in 2021. 17:45

  • Need for more autopsies to understand the low-grade inflammatory process and potential alternative treatments. 18:21

  • Anticipation of future viral triggers and the importance of studying potential responses beforehand. 19:27

  • Consideration of the risk to vaccinated individuals and the need for proactive mitigation strategies. 19:35

  • Hope for a future where medical practice is not influenced by external factors like politics and finance. 20:07