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Exploring the impact of autoimmunity in different stages of Covid-19 progression.
  • Autoimmunity can turn the body’s protector into its persecutor. 3:18

  • Understanding the role of serum/plasma A2 in autoimmunity is crucial. 3:33

  • Autoimmunity to A2 and other proteins can have significant implications. 3:41

  • Different stages of Covid-19 progression include asymptomatic/mild cases, bronchitis, viral pneumonia, moderate Covid, and severe pneumonia. 4:15

  • Severe Covid cases may involve a combination of viral pneumonia and microclots. 5:09

Understanding the relationship between viruses and autoimmune diseases, specifically in the context of severe Covid-19.
  • Autoimmunity occurs when antibodies target the body’s own cells, leading to inflammation and damage. 5:57

  • Viral mediated autoimmune diseases are well-known, with various viruses linked to triggering autoimmune responses in diseases like multiple sclerosis and rheumatoid arthritis. 7:25

  • The hypothesis that Covid-19 is a viral mediated autoimmune disease was explored in early 2020 to improve treatment approaches and save lives. 9:00

  • Research focused on autoantibodies to ACE2, the entry receptor for the virus, to understand the autoimmune response to Covid-19. 9:52

  • Papers were published in 2020 and 2021 outlining the theory of autoimmunity to ACE2, highlighting the importance of understanding the autoimmune response in severe Covid-19 cases. 10:11

  • Challenges in research funding and publication delays were faced, but the importance of studying the autoimmune response in Covid-19 remained crucial for long-term health outcomes. 11:00

Insights on the atypical autoimmune response in Covid-19 and its impact on disease severity.
  • Auto antibodies to ace2 associated with severe Covid-1. 11:25

  • Presence of elevated IGG and IGA Auto antibodies in severe Covid-19 case. 12:38

  • Unusual characteristics of Covid-19 including varying symptoms and sex-based mortality rate difference. 14:05

  • Higher risk of hospitalization in elderly, racial disparities, and association with hypertension and obesit. 15:20

  • Clinical observations suggesting Covid-19’s unique mechanism compared to typical respiratory viruse. 16:22

Insights on autoimmune response in severe COVID-19 cases and potential risk factors.
  • Spike proteins on the virus play a crucial role in cell entry. 16:31

  • Differentiating viral pneumonia from moderate to severe COVID-19 is important. 17:52

  • Viral phase of the disease can be asymptomatic but still cause significant lung inflammation. 19:39

  • Elevated levels of free Ace 2 in the bloodstream may be linked to severe COVID-19 cases. 21:38

Understanding the autoimmune response in severe Covid-19 cases.
  • Inflammation of blood vessels leads to microclots in severe Covid-19. 21:55

  • Differentiating types of severe Covid-19 based on symptoms and progression. 22:20

  • Consistency in antibody response timing and presentation of severe disease. 23:39

  • Autoimmunity causing the body’s protector to become its persecutor. 24:41

  • Link provided for Co Advance 360 pre-launch sale. 24:58

  • Importance of joining the webinar for further discussion. 25:06