Exploring the impact of autoimmunity in different stages of Covid-19 progression.
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Autoimmunity can turn the body’s protector into its persecutor. • 3:18
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Understanding the role of serum/plasma A2 in autoimmunity is crucial. • 3:33
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Autoimmunity to A2 and other proteins can have significant implications. • 3:41
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Different stages of Covid-19 progression include asymptomatic/mild cases, bronchitis, viral pneumonia, moderate Covid, and severe pneumonia. • 4:15
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Severe Covid cases may involve a combination of viral pneumonia and microclots. • 5:09
Understanding the relationship between viruses and autoimmune diseases, specifically in the context of severe Covid-19.
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Autoimmunity occurs when antibodies target the body’s own cells, leading to inflammation and damage. • 5:57
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Viral mediated autoimmune diseases are well-known, with various viruses linked to triggering autoimmune responses in diseases like multiple sclerosis and rheumatoid arthritis. • 7:25
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The hypothesis that Covid-19 is a viral mediated autoimmune disease was explored in early 2020 to improve treatment approaches and save lives. • 9:00
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Research focused on autoantibodies to ACE2, the entry receptor for the virus, to understand the autoimmune response to Covid-19. • 9:52
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Papers were published in 2020 and 2021 outlining the theory of autoimmunity to ACE2, highlighting the importance of understanding the autoimmune response in severe Covid-19 cases. • 10:11
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Challenges in research funding and publication delays were faced, but the importance of studying the autoimmune response in Covid-19 remained crucial for long-term health outcomes. • 11:00
Insights on the atypical autoimmune response in Covid-19 and its impact on disease severity.
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Auto antibodies to ace2 associated with severe Covid-1. • 11:25
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Presence of elevated IGG and IGA Auto antibodies in severe Covid-19 case. • 12:38
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Unusual characteristics of Covid-19 including varying symptoms and sex-based mortality rate difference. • 14:05
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Higher risk of hospitalization in elderly, racial disparities, and association with hypertension and obesit. • 15:20
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Clinical observations suggesting Covid-19’s unique mechanism compared to typical respiratory viruse. • 16:22
Insights on autoimmune response in severe COVID-19 cases and potential risk factors.
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Spike proteins on the virus play a crucial role in cell entry. • 16:31
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Differentiating viral pneumonia from moderate to severe COVID-19 is important. • 17:52
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Viral phase of the disease can be asymptomatic but still cause significant lung inflammation. • 19:39
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Elevated levels of free Ace 2 in the bloodstream may be linked to severe COVID-19 cases. • 21:38
Understanding the autoimmune response in severe Covid-19 cases.
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Inflammation of blood vessels leads to microclots in severe Covid-19. • 21:55
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Differentiating types of severe Covid-19 based on symptoms and progression. • 22:20
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Consistency in antibody response timing and presentation of severe disease. • 23:39
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Autoimmunity causing the body’s protector to become its persecutor. • 24:41
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Link provided for Co Advance 360 pre-launch sale. • 24:58
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Importance of joining the webinar for further discussion. • 25:06